Electronic Portfolios in the Classroom: Factors Impacting Teachers’ Integration of New Technologies and New Pedagogies

This article presents the findings of a study on the use of an electronic portfolio (EP) in 16 elementary classrooms across Canada. Using a mixed-methods approach, data were collected to understand how teachers used EPs in their classrooms, to what extent they integrated the EP into their practice, and the factors influencing their use. Using expectancy theory, findings indicate that low implementers experienced significant technical obstacles and/or were reluctant to change their established practices, whereas high implementers reported feeling supported by their administration, experiencing growth in their teaching practice, and using more pedagogical practices that support self-regulated learning as a result of the scaffolding provided by the software

Modelling farm vulnerability to flooding: towards the appraisal of vulnerability mitigation policies

In France, two new kinds of flood management policies are promoted: floodplain restoration and vulnerability mitigation. Few experience feedback exist on these policies but they may have strong impacts on farms. Flood management on Rhône River is highly illustrative of these policies and local authorities would like to appraise the efficiency of these policies with an economic tool (Cost-Benefit Analysis) to help decision making. But the current methods of flood damage modelling do not make the appraisal of these policies possible; mainly because they do not take into account the organizational and temporal dimensions of damage formation and propagation at farm scale. After a presentation of the Rhône River context and policies, we review existing methods of flood damage modelling for agriculture and show the interest to focus on the farm scale instead of land plot scale. Based upon the theoretical frameworks for systemic approach, we detail the construction of our conceptual model of farm vulnerability before presenting a case study that shows how the model can be implemented to compute flood damage at farm scale. Finally, the outlooks concerning the use of the model to appraise vulnerability mitigation policies and its application at regional scale are developed.Modélisation;Vulnérabilité;Langage UML;Évaluation des risques;Exploitation agricole;Inondation

The effects of ABRACADABRA on reading outcomes : an updated meta-analysis and landscape review of applied field research

A Balanced Reading Approach for Children Designed to Achieve Best Results for All (ABRA) is an evidence-based suite of interactive multimedia that engages learners in the development of core reading skills. This detailed meta-analysis presents an update on research evidence about the effectiveness of ABRA for elementary students. Offering distinct environments (or modules) for students, teachers and parents, ABRA is neither linear in use nor prescriptive of a single concept or method of teaching and learning to read. The results of the analysis provide positive evidence of the value of ABRA as a tool to promote development of early literacy skills. Includes bibliography

Endocytosis of the Anthrax Toxin Is Mediated by Clathrin, Actin and Unconventional Adaptors

The anthrax toxin is a tripartite toxin, where the two enzymatic subunits require the third subunit, the protective antigen (PA), to interact with cells and be escorted to their cytoplasmic targets. PA binds to cells via one of two receptors, TEM8 and CMG2. Interestingly, the toxin times and triggers its own endocytosis, in particular through the heptamerization of PA. Here we show that PA triggers the ubiquitination of its receptors in a β-arrestin-dependent manner and that this step is required for clathrin-mediated endocytosis. In addition, we find that endocytosis is dependent on the heterotetrameric adaptor AP-1 but not the more conventional AP-2. Finally, we show that endocytosis of PA is strongly dependent on actin. Unexpectedly, actin was also found to be essential for efficient heptamerization of PA, but only when bound to one of its 2 receptors, TEM8, due to the active organization of TEM8 into actin-dependent domains. Endocytic pathways are highly modular systems. Here we identify some of the key players that allow efficient heptamerization of PA and subsequent ubiquitin-dependent, clathrin-mediated endocytosis of the anthrax toxin

Caractérisation des stratégies de gestion pour la modélisation de la vulnérabilité des exploitations agricoles aux inondations : Lier les dimensions spatiale, organisationnelle et temporelle d'un système complexe

Les politiques publiques de gestion des inondations s'orientent vers la restauration des champs d'expansion de crue et de réduction de la vulnérabilité, qui auront un impact important sur les exploitations agricoles. L'évaluation des effets de ces politiques sur les exploitations agricoles n'est pas envisageable avec les méthodologies actuelles et le retour d'expérience quasiment inexistant. Il était donc nécessaire de développer un modèle de simulation des dommages directs et induits en prenant en compte la dimension systémique de l'exploitation agricole. Pour cela, nous proposons un modèle conceptuel de la vulnérabilité à l'échelle de l'exploitation agricole et montrons comment il nous a permis de mettre en évidence l'importance des stratégies de gestion post-inondation pour la modélisation des dommages. Nous présentons ensuite les résultats des enquêtes réalisées sur les exploitations arboricoles de la zone aval du Rhône pour la caractérisation de ces stratégies. Enfin, nous montrons comment nous avons intégré dans le modèle de simulation des dommages, les données recueillies par enquêtes. Les premiers résultats de simulation des dommages confirment l'importance de prendre en compte les effets induits de l'inondation sur le système " exploitation agricole ". En perspective, l'utilisation du modèle de simulation des dommages dans le cadre d'une évaluation économique des politiques de réduction de la vulnérabilité des exploitations agricoles sur la zone aval du Rhône est discutée.INONDATION;POLITIQUE PUBLIQUE;EXPLOITATION AGRICOLE;VULNERABILITE;SIMULATION;STRATEGIE

Use of ELM software to teach and learn mathematics in grade-one Kenyan classrooms : a brief report of the 2019 study

The Kenyan government mandates one digital device per child in elementary grades, making it possible to test if the need for early numeracy intervention can be addressed by introducing Emerging Literacy in Mathematics (ELM) software in teaching and learning mathematics. This brief reports on the study conducted in 14 grade-one classes from 7 primary public schools in Mombasa area (2019). Designed as a strong test of ELM, it unfolded in authentic classroom conditions. Outcomes strongly suggest that the use of ELM significantly improved young students’ mathematical abilities over those of students from the control group

The effects of ubiquitous computing on student learning: A systematic review. E-Learn 2007

Abstract: As technology use in education increases, interest in and implementations of ubiquitous computing initiatives have also increased. One-toone laptop initiatives have sprung up throughout North America at the school, district, and state or province levels. This paper is an attempt to synthesize available studies of one-to-one initiatives at the K-12 level using both quantitative and narrative techniques. It is hoped that by so doing, best practices of these types of implementations can be identified

Late Endosomal Cholesterol Accumulation Leads to Impaired Intra-Endosomal Trafficking

Background Pathological accumulation of cholesterol in late endosomes is observed in lysosomal storage diseases such as Niemann-Pick type C. We here analyzed the effects of cholesterol accumulation in NPC cells, or as phenocopied by the drug U18666A, on late endosomes membrane organization and dynamics. Methodology/Principal Findings Cholesterol accumulation did not lead to an increase in the raft to non-raft membrane ratio as anticipated. Strikingly, we observed a 2–3 fold increase in the size of the compartment. Most importantly, properties and dynamics of late endosomal intralumenal vesicles were altered as revealed by reduced late endosomal vacuolation induced by the mutant pore-forming toxin ASSP, reduced intoxication by the anthrax lethal toxin and inhibition of infection by the Vesicular Stomatitis Virus. Conclusions/Significance These results suggest that back fusion of intralumenal vesicles with the limiting membrane of late endosomes is dramatically perturbed upon cholesterol accumulation

CMG2/ANTXR2 regulates extracellular collagen VI which accumulates in hyaline fibromatosis syndrome.

Loss-of-function mutations in capillary morphogenesis gene 2 (CMG2/ANTXR2), a transmembrane surface protein, cause hyaline fibromatosis syndrome (HFS), a severe genetic disorder that is characterized by large subcutaneous nodules, gingival hypertrophy and severe painful joint contracture. Here we show that CMG2 is an important regulator of collagen VI homoeostasis. CMG2 loss of function promotes accumulation of collagen VI in patients, leading in particular to nodule formation. Similarly, collagen VI accumulates massively in uteri of Antxr2 <sup>-/-</sup> mice, which do not display changes in collagen gene expression, and leads to progressive fibrosis and sterility. Crossing Antxr2 <sup>-/-</sup> with Col6a1 <sup>-/-</sup> mice leads to restoration of uterine structure and reversion of female infertility. We also demonstrate that CMG2 may act as a signalling receptor for collagen VI and mediates its intracellular degradation

Promoting young Kenyans’ growth in literacy with educational technology : a tale of two years of implementation

The study explored impacts of the interactive early literacy software, ABRACADABRA (A Balanced Reading Approach for Children Always Designed to Achieve Best Results for All, ABRA) and the digital library, READS, on primary students’ reading abilities and reading instruction in Kenyan schools. ABRA is an online application that provides an engaging interactive environment for learning literacy for early elementary school-aged children. Embedded in the “Learning Toolkit Plus,” READS (Repository for E-Books and Digital Stories) is a searchable collection of multi-lingual stories available online. As a result of exposure to ABRA and READS, the gap between high and low performing students diminished.Department of Foreign Affairs, Trade and Development (DFATD)Aga Khan Foundation Canada (AKFC)Social Sciences and Humanities Research Council (SSHRC) of Canad